So far, Samuel L. Jackson's Nick Fury has appeared in eleven MCU films, starting with the first MCU film in 2008's Iron Man, with the latest being his appearance in 2019's Spider-Man: Far From Home.
You can pencil in Jackson's twelfth appearance when The Marvels premieres in November 2022.
Death, Taxes, and Samuel L. Jackson
In terms of the MCU timeline, the earliest appearance of Samuel L. Jackson in the Marvel Cinematic Universe is in 2019's Captain Marvel.
The Brie Larson-led movie treated audiences to a rare look at Nick Fury with both eyes still intact, as he finds out that the world is full of superpowered beings after meeting with Larson's Carol Danvers, who is also known as Captain Marvel.
